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     Intralesional steroid therapy

Intralesional steroid therapy

Intralesional steroid injection involves a corticosteroid such as triamcinolone acetonide suspension injected directly into a lesion on or immediately below the skin.

Intralesional steroid injection may be indicated for the following skin conditions:

  • Alopecia areata
  • Keloids/hypertrophic scars
  • Hypertrophic lichen planus
  • Lichen simplex chronicus (neurodermatitis)
  • Localised psoriasis
  • Acne cysts (see nodulocystic acne)

The treated area is likely to blister within a few hours. Sometimes the blister is clear and sometimes it is red or purple because of bleeding (this is harmless). Treatment near the eye may result in a puffy eyelid, especially the following morning, but the swelling settles within a few days. Within a few days a scab forms and the blister gradually dries up.

The advantages of Intralesional therapy is that it delivers a high concentration of drug directly in the affected area thereby offering a faster resolution of the condition.

Intralesional triamcinolone is injected directly into the skin lesion using a fine needle after cleaning the site of injection with alcohol or antiseptic solution. The initial dose per injection site will vary depending on the lesion being treated. Generally, 0.1 mL is injected per square centimetre of involved skin. It can be repeated every 4-8 weeks.

Rarely Intralesional injections can cause adverse effects. These include pain, bleeding, bruising and infection. Rarely delayed adverse effects such as atrophy appearing as skin indentations or dimples white marks (leukoderma),brown marks (postinflammatory pigmentation),or small dilated blood vessels may develop at or around the site of injection- these usually resolve or may occasionally persist long term.

         
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Disha Skin & Laser Institute
Shrusti Prime, 1st Floor , Above S. Kumar Jewellers, Gokhale Road, Thane (W),
Maharashtra - India
Contact : +91 932 16 32 000,  022 - 25335066 / 77 E-mail : dishastaff@gmail.com
 
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